Respiratory Syncytial Virus

MAb Target

RSV Subtype

Comments

3.5 phosphoprotein VPP32 subtypes A and B Tested by Immunoblot and IF
4.14 phosphoprotein VPP32 subtype B only Tested by Immunoblot and IF
4.15 fusion glycoprotein VGP70 subtypes A and B  Neutralises viral infectivity (20 fold reduction)
4.18 nucleoprotein VPN41 subtype B Tested by Immunoblot

 

 

MAb Target

RSV Subtype

Comments

11-2-D2 GP90 (G-glycoprotein VP90) subtype A Enhances in vitro RSV infection of human macrophages
11-5-G9 fusion glycoprotein VGP70 subtype A Tested by immunoblot, no neutralising activity
11-6-F9 fusion glycoprotein VGP70 subtype A Neutralises viral infectivity (20 fold reduction)
11-2-C9 fusion glycoprotein VGP70 subtype A Neutralises viral infectivity (100 fold reduction)
11-2-F3 fusion glycoprotein VGP48/VGP70 subtype A Neutralises viral infectivity (160 fold reduction)
11-3-A3 fusion glycoprotein VGP48/VGP70 subtypes A and B Neutralises viral infectivity (1000 fold reduction)