Scottish Fish Immunology Research Centre Presentation
Yehfang Hu (Scottish Fish Immunology Research Centre, University of Aberdeen) attended the International Conference on Fish and Shellfish Immunology in Gran Canaria, Spain. Yehfang Hu gave a presentation entitled: Induction of IL-22 protein and IL-22-producing cells in rainbow trout Oncorhynchus mykiss.
Two monoclonal antibodies to salmonid IL-22 were produced to investigate the cells and sites of IL-22 production, as well as to measure IL-22 secretion in this species. The mAbs were used in a variety of assays including ELISA, western blot, flow cytometry and immunohistochemistry. The main interest of the study was on mucosal defences and whether IL-22 protein expression is upregulated in response to bacterial infection.